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In contrast, the comparison of the lipid profiles between the HFD group and the HFD + EPA group showed significant increases in EPA, Docosahexaenoic acid (22:6n-3) (DHA), and docosapentaenoate (DPA) (22:5n-3), and significant decreases in stearate and arachidonate (20:4n-6) in the latter group (Table 3)

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Randomized controlled trials show oral semaglutide produces 7-15% body weight reduction over 68 weeks, with consistent improvements in blood sugar control and cardiovascular markers

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